Enplas is an innovative manufacturing partner for global providers and emerging startups across the life science industry. With extensive product development experience and R&D activities, Enplas’s depository of design transition expertise helps customers overcome their DFM bottlenecks and enhance their device’s performance.
Explore our Innovation Lab investigations or contact us for insights into how our design development ideas streamline life science applications with simple-yet-effective solutions.
Automate On-Chip DNA Library Prep Without Bulky Instruments:
Large instruments with complex tubing are often required to automate DNA library preparation for NGS and other genetic analyses. This makes the system complex, cumbersome, and expensive. The RMVP system is versatile and can be customized freely to meet your unique application needs. In this example, the Enplas RMVP system achieved the automation of the end prep process of a DNA library prep, which included PCR, size selection, and beads isolation by magnets, all on one chip, within a handheld-sized device.
On-Chip DNA Purification and Amplification with Minimum Equipment:
Integrating conventional DNA/RNA analysis methods into a microfluidic system can lead to exceedingly large, costly, and power-hungry systems. Instead, combine various DNA/RNA analysis methods on a single chip. Using simple microfluidic handling features, you can accurately drive and move fluids while minimizing device footprint, power consumption, complexity, cross-contamination, and equipment cost. For example, a closed on-chip valve and pump system drives and mixes reagents in a thermal chamber and uses a Peltier unit to apply thermal cycles. DNA purification is easily achieved with on-chip magnets isolating magnetic beads.
Multiplex Metering on Microfluidic Chips Without Complex Tubing:
Special Chip Features with an On-Chip Pump and Valve
Automating multiplex fluid metering can be achieved without complicated routing of pumps, syringes, and tubes. This microfluidic chip design concept enables automated metering of various liquid volumes without the complex tubing: A simple combination of an on-chip valve and pump system, measuring chambers on chip, an optical liquid surface detection system, and microfluidic channel surface treatments.